Recommendations for Risk Categorization and Prophylaxis of Invasive Fungal Diseases in Hematological Malignancies:  A Critical Review of Evidence and Expert Opinion (TEO-4)

Bo�a, Can; Bolaman, Zahit; �a��rgan, Se�kin; Karado�an, �hsan; �zcan, Mehmet Ali; �zkalemka�, Fahir; Saba, Rabin; S�nmez, Mehmet; �enol, Esin; Akan, Hamdi; Akova, Murat

Recommendations for Risk Categorization and Prophylaxis of Invasive Fungal Diseases in Hematological Malignancies: A Critical Review of Evidence and Expert Opinion (TEO-4) [Turk J Hematol]

Turk J Hematol. 2015; 32(2): 100-117 | DOI: 10.4274/tjh.2014.0277

Recommendations for Risk Categorization and Prophylaxis of Invasive Fungal Diseases in Hematological Malignancies: A Critical Review of Evidence and Expert Opinion (TEO-4)

Can Bo�a¹, Zahit Bolaman², Se�kin �a��rgan³, �hsan Karado�an⁴, Mehmet Ali �zcan⁵, Fahir �zkalemka�⁶, Rabin Saba⁷, Mehmet S�nmez⁸, Esin �enol⁹, Hamdi Akan¹⁰, Murat Akova¹¹
¹Ba�kent University Hospital, Faculty Of Medicine, Department Of Hematology, Adana
²Adnan Menderes University, Faculty Of Medicine, Division Of Hematology, Aydin
³Medicalpark �zmir Hospital, Department Of Hematology And Bone Marrow Transplantation Center, �zmir
⁴Medstar Antalya Hospital, Department Of Hematology And Stem Cell Transplantation Unit, Antalya
⁵9 Eyl�l University, Faculty Of Medicine, Department Of Hematology, �zmir
⁶Uluda� University Faculty Of Medicine, Department Of Infectious Diseases And Clinical Microbiology, Bursa
⁷Medstar Antalya Hospital, Department Of Infectious Disease, Antalya
⁸Karadeniz Technical University, Faculty Of Medicine, Department Of Hematology, Trabzon
⁹Gazi University Faculty Of Medicine, Department Of Infectious Diseases, Ankara
¹⁰Ankara University Faculty Of Medicine, Cebeci Campus, Department Of Hematology, Cebeci, Ankara, Turkey
¹¹Hacettepe University, Faculty Of Medicine, Department Of Infectious Diseases, Ankara

This is the last of a series of articles on invasive fungal infections prepared by opinion leaders in Turkey. The aim of these articles is to guide clinicians in managing invasive fungal diseases in hematological malignancies and stem cell transplantation based on the available best evidence in this field. The previous articles summarized the diagnosis and treatment of invasive fungal disease and this article aims to explain the risk categorization and guide the antifungal prophylaxis in invasive fungal disease.

Keywords: Hematological malignancy, Invasive fungal infections, Prophylaxis, Risk

Hematolojik Malignitelerdeki �nvazif Fungal Enfeksiyon Riskinin Belirlenmesi ve Profilaksi: Kan�tlara Ele�tirel Bak�� ve T�rk Uzman G�r��leri (TUG-4)

Bu makale T�rkiye�de invazif fungal enfeksiyon ile u�ra�an uzmanlar taraf�ndan haz�rlanan bir seri yaz�n�n sonuncusudur. Bu makaleler hematolojik malignitelerde ve k�k h�cre nakli hastalar�nda invazif fungal hastal�klar�n y�netimini eldeki kan�tlar�n ��nda en iyi hale getirmeyi ama�lamaktad�r. �lk yaz�lar tan� ve tedaviyi �zetlerken, bu makale invazif fungal hastal�kta risk kategorizasyonu ve profilaksiyi ele almaktad�r.

Anahtar Kelimeler: Hematolojik malignite, �nvazif fungal enfeksiyon, Profilaksi, Risk

Can Bo�a, Zahit Bolaman, Se�kin �a��rgan, �hsan Karado�an, Mehmet Ali �zcan, Fahir �zkalemka�, Rabin Saba, Mehmet S�nmez, Esin �enol, Hamdi Akan, Murat Akova. Recommendations for Risk Categorization and Prophylaxis of Invasive Fungal Diseases in Hematological Malignancies: A Critical Review of Evidence and Expert Opinion (TEO-4). Turk J Hematol. 2015; 32(2): 100-117

Corresponding Author: Hamdi Akan, T�rkiye

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