E-ISSN: 1308-5263
Primary Uterine Lymphoma: A Rare Cause of Postmenopausal Bleeding [Turk J Hematol]
Turk J Hematol. 2004; 21(1): 39-43

Primary Uterine Lymphoma: A Rare Cause of Postmenopausal Bleeding

Cem Dane, Banu Dane, Emine Kalli, Murat Erginbaş, Ahmet Çetin
Haseki Education And Research Hospital, Gynecology And Obstetrics, Istanbul, Turkey

Although uterus and cervix infiltration is a frequent finding in the later stages of lymphomatous disease, non-Hodgkin’s lymphoma (NHL) of the female genital tract is extremely rare. We present the case of a 63-years- old woman diagnosed with postmenopausal bleeding, Ann Arbor stage IE, primary, diffuse, large B-cell NHL of the uterus. Disease status was monitored with physical examination and imaging studies. We administered chemotherapy according to CHOP protocol (cyclophosphamide, adriamycin, vincristine, and prednisone). Primary pelvic NHL may present symptoms like other more common gynecologic cancers. It should be considered in the differential diagnosis of gynecologic malignancy. Our case emphasizes the importance of chemotherapy that can provide a control of the distant microscopic metastases.

Keywords: Lymphoma, Uterus, Bleeding.


Primer Uterus Lenfoması: Seyrek Görülen Bir Menopoz Sonrası Kanama Nedeni

Cem Dane, Banu Dane, Emine Kalli, Murat Erginbaş, Ahmet Çetin
Haseki Education And Research Hospital, Gynecology And Obstetrics, Istanbul, Turkey

Lenfomanın ileri evrelerinde uterus ve serviks infiltrasyonu sık bulgu ise de, kadın genital sistem non-Hodgkin-lenfoması çok nadirdir. Burada 63 yaşında postmenopozal kanama ile Ann Arbor Evre IE, primer, difüz, büyük B-hücreli uterus lenfoması tanısı konan bir hastayı sunmaktayız. Hasta CHOP protokolü verilerek tedavi edildi. Primer pelvik NHL, diğer jinekolojik kanserlere benzeyen belirtilerle gelir ve jinekolojik malignitelerin ayırıcı tanısında düşünülmelidir. Bu olgu kemoterapinin uzak mikroskobik metastazları kontrol etmesindeki önemini vurgulamaktadır.

Anahtar Kelimeler: Lenfoma, Uterus, Kanama.


Cem Dane, Banu Dane, Emine Kalli, Murat Erginbaş, Ahmet Çetin. Primary Uterine Lymphoma: A Rare Cause of Postmenopausal Bleeding. Turk J Hematol. 2004; 21(1): 39-43

Corresponding Author: Cem Dane, Türkiye


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