Gum hypertrophy - an unusual presenting feature in a case of precursor T-cell acute lymphoblastic leukemiaChennagiri Srinivasamurthy Premalata1, Davanam Satyanarayana Madhumati1, Vishweshwariah Lakshmidevi1, Rudramurthy Pradeep1, Lingappa Appaji2, Geetashree Mukherjee11Department Of Pathology, Kidwai Memorial Institute Of Oncology,bangalore, India
2Department Of Pediatric Oncology,kidwai Memorial Institute Of Oncology,bangalore, India
Acute lymphoblastic leukemia/lymphoma, the malignant transformation of T-cell or B-cell precursors, is the most common diagnosis in pediatric oncology. Precursor T-cell acute lymphoblastic leukemia/lymphoma commonly affects adolescents, and is associated with mediastinal mass in over half of the cases, with early dissemination to bone marrow, gonads and the central nervous system. We present a rare case of precursor T-cell acute lymphoblastic leukemia/lymphoma with initial oral manifestation, presenting with the unusual features of gum hypertrophy and involvement of upper jaw and palate in a 10-year-old boy. This report discusses the clinical presentation, histopathologic and immunologic features, and diagnosis of this malignancy. Keywords: Precursor T-ALL, gum, jaw, oral cavity
Diş eti hipertrofisi ile giden bir prekürsör T hücreli akut lenfoblastik lösemi olgusuChennagiri Srinivasamurthy Premalata1, Davanam Satyanarayana Madhumati1, Vishweshwariah Lakshmidevi1, Rudramurthy Pradeep1, Lingappa Appaji2, Geetashree Mukherjee11Department Of Pathology, Kidwai Memorial Institute Of Oncology,bangalore, India
2Department Of Pediatric Oncology,kidwai Memorial Institute Of Oncology,bangalore, India
T veya B hücre öncüllerinin malin transformasyonu sonucu oluşan akut lenfoblastik lösemi/lenfoma pediatrik onkolojinin en sık rastlanılan hastalığıdır. Prekürsör T hücreli akut lenfoblastik lösemi/lenfoma sıklıkla adölesan çağda görülür; olguların yarısından çoğunda mediastinal kütle ve buna eşlik eden kemik iliği, gonad ve merkezi sinir sistemi tutulumu mevcuttur. Bu yazıda, 10 yaşında bir erkek çocukta dişeti hipertrofisi, üst çene kemiği ve damak tutulumu ile ortaya çıkan nadir bir öncül T hücreli akut lenfoblastik lösemi/lenfoma olgusu sunulmaktadır. Olgu vasıtasıyla bu malinitenin klinik bulguları, histopatolojik ve immünolojik özellikleri ve ayırıcı tanısı tartışılmıştır. Anahtar Kelimeler: Prekürsör T-ALL, diş eti, çene, ağıziçi boşluğu.
Chennagiri Srinivasamurthy Premalata, Davanam Satyanarayana Madhumati, Vishweshwariah Lakshmidevi, Rudramurthy Pradeep, Lingappa Appaji, Geetashree Mukherjee. Gum hypertrophy - an unusual presenting feature in a case of precursor T-cell acute lymphoblastic leukemia. Turk J Hematol. 2008; 25(4): 201-204
Corresponding Author: Chennagiri Srinivasamurthy Premalata, India |
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