Prothrombin G20210A and A19911G mutations in Turkish pediatric stroke patients

Yıldız, Züleyha; Deda, Gülhis; Akar, Nejat

Prothrombin G20210A and A19911G mutations in Turkish pediatric stroke patients [Turk J Hematol]

Turk J Hematol. 2006; 23(4): 197-199

Prothrombin G20210A and A19911G mutations in Turkish pediatric stroke patients

Züleyha Yıldız¹, Gülhis Deda², Nejat Akar¹
¹Department Of Pediatric Molecular Genetics, Ankara University Faculty Of Medicine, Ankara, Turkey
²Department Of Pediatric Neurology, Ankara University Faculty Of Medicine, Ankara, Turkey

Effects of PT A19911G polymorphism in Turkish pediatric stroke patients were investigated. The case-control study included 107 patients with cerebral infarct and 83 healthy unrelated controls. Distribution of PT A19911G and data on the combined effect of PT 19911G and PT 20210A alleles do not indicate that they constitute a risk in this group of patients.

Keywords: Pediatric stroke, PT A19911G, PT G20210A

Türk pediatrik inme hastalarında protrombin G20210A ve A19911G mutasyonları

Züleyha Yıldız¹, Gülhis Deda², Nejat Akar¹
¹Department Of Pediatric Molecular Genetics, Ankara University Faculty Of Medicine, Ankara
²Department Of Pediatric Neurology, Ankara University Faculty Of Medicine, Ankara

Türk pediatrik inme hastalarında Protrombin G20210A ve A19911G mutasyonları ve PT A19911G polimorfizminin etkisi araştırıldı. Vaka-kontrol çalışmasına 107 serebral infarktlı hasta ve 83 sağlıklı akraba olmayan kontrol grubu dahil edildi. Bu çalışma grubunda PT A19911G polimorfizminin dağılımı ve PT 19911G ile 20210A allelerinin etkisi birlikte değerlendirildiğinde bir risk oluşturmadıkları saptanmıştır.

Anahtar Kelimeler: Pediatrik inme, PT A19911G, PT G20210A

Corresponding Author: Nejat Akar, Türkiye
Manuscript Language: English

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