Turk J Hematol. 2001; 18(3): 195-197

Homozygous ß-Thalassemia Associated with Familial Mediterranean Fever in a Turkish Patient

Duran Canatan¹, Rüya Coşan¹, Hakkı Taştan², Onur Bilenoğlu³, A. Nazlı Başak^3
1Thalassemia Center, Antalya State Hospital, Antalya, Turkey
²Department Of Pediatric Molecular Genetics, Ankara University, Ankara, Turkey
³Department Of Molecular Biology And Genetics, Boğaziçi University, İstanbul, Turkey

We report here a ß- thalassemia major case (homozygous IVS-1-110 G-A) associated with Familial Mediterranean Fever (FMF) (homozygous 694 Met-Val). Our patient’s clinical course revealed a possible synergistic effect between colchicine and desferrioxamine (DFO) However, this could be a only a coincidence, as under colchicine therapy, fever attacks may appear, this may be the topic of a further investigation.

Keywords: Thalassemia, Familial Mediterranean Fever (FMF), Desferrioxamine (DFO), Colchicine.

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