Coexistence of Two Prothrombotic Mutations, Factor V 1691 G-A and Prothrombin 20210 G-A, and the Risk of Thrombosis in Turkish Population

Coexistence of Two Prothrombotic Mutations, Factor V 1691 G-A and Prothrombin 20210 G-A, and the Risk of Thrombosis in Turkish Population [Turk J Hematol]

Turk J Hematol. 2003; 20(1): 31-33

Coexistence of Two Prothrombotic Mutations, Factor V 1691 G-A and Prothrombin 20210 G-A, and the Risk of Thrombosis in Turkish Population

Nejat Akar, Erkan Y�lmaz, Ece Akar
The Pediatric Molecular Genetics Department Of The Ankara University, Ankara, Turkey

This report summarizes the coexistence of two mutations; Factor V 1691 G-A and prothrombin 20210 G-A in Turkish population and emphasises on the point that, this coexistence increases the risk of thrombosis in such patients. In thrombophilia screening programs, these two variants should be included, particularly in Turkish population.

Keywords: Factor V gene, Prothrombin gene, Thrombosis.

�ki Protrombotik Mutasyonun (Fakt�r V 1691 G-A ve Protrombin 20210 G-A) Birlikteli�i ve T�rk Toplumunda Tromboz Riski

Nejat Akar, Erkan Y�lmaz, Ece Akar
The Pediatric Molecular Genetics Department Of The Ankara Universitesi, Ankara, Turkiye

Bu yaz�da T�rk toplumunda Fakt�r V 1691 G-A ve protrombin 20210 G-A mutasyonlar�n�n birarada bulunma s�kl�� zetlenmekte ve bu birlikteli�in tromboz riskini artt�rd�� vurgulanmaktad�r. T�rk toplumu trombofili tarama programlar� i�in bu iki varyant eklenmelidir.

Anahtar Kelimeler: Fakt�r V geni, Protrombin geni, Tromboz. Turk J Haematol

Nejat Akar, Erkan Y�lmaz, Ece Akar. Coexistence of Two Prothrombotic Mutations, Factor V 1691 G-A and Prothrombin 20210 G-A, and the Risk of Thrombosis in Turkish Population. Turk J Hematol. 2003; 20(1): 31-33

Corresponding Author: Nejat Akar, T�rkiye

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