Mixed Intravascular and Extravascular Hemolysis Despite Eculizumab in Paroxysmal Nocturnal Hemoglobinuria: A Case of Switching to Pegcetacoplan

Demircioğlu, Sinan

Mixed Intravascular and Extravascular Hemolysis Despite Eculizumab in Paroxysmal Nocturnal Hemoglobinuria: A Case of Switching to Pegcetacoplan [Turk J Hematol]

Turk J Hematol. Ahead of Print: TJH-97404 | DOI: 10.4274/tjh.galenos.2026.97404

Mixed Intravascular and Extravascular Hemolysis Despite Eculizumab in Paroxysmal Nocturnal Hemoglobinuria: A Case of Switching to Pegcetacoplan

Sinan Demircioğlu
Necmettin Erbakan University Faculty of Medicine, Department of Hematology, Konya, Türkiye

Keywords: Paroxysmal nocturnal hemoglobinuria, Pegcetacoplan, Eculizumab, C3 inhibition, Extravascular hemolysis, C3d positivity

Paroksismal Noktürnal Hemoglobinüride Ekulizumaba Rağmen Devam Eden Miks İntravasküler ve Ekstravasküler Hemoliz: Pegsetakoplana Geçilen Bir Olgu

Sinan Demircioğlu
Necmettin Erbakan Üniversitesi, Tıp Fakültesi, Hematoloji Bilim Dalı, Konya, Türkiye

Anahtar Kelimeler: Paroksismal noktürnal hemoglobinüri, Pegsetakoplan, Ekulizumab, C3 inhibisyonu, Ekstravasküler hemoliz, C3d pozitifliği

Corresponding Author: Sinan Demircioğlu, Türkiye
Manuscript Language: English

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